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商品详细nbome/Ergoline-8-carboxamide, 9,10-didehydro-6-methyl-N-(1-methylpropyl)-, [8b(R)]-, (Z)-2-butenedioate (1:1)/T/T|Westem Unio
nbome/Ergoline-8-carboxamide, 9,10-didehydro-6-methyl-N-(1-methylpropyl)-, [8b(R)]-, (Z)-2-butenedioate (1:1)/T/T|Westem Unio
nbome/Ergoline-8-carboxamide, 9,10-didehydro-6-methyl-N-(1-methylpropyl)-, [8b(R)]-, (Z)-2-butenedioate (1:1)/T/T|Westem Unio
商品编号: 137765-83-4
品牌: nbome
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产地: Germany
公司: Nbome-trade gmbh.
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公司分类: Others
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商品介绍

Lysergicacid2-butylamide(2-Butyllysergamide,LSB)isananalogueoriginallydevelopedbyRichardPiochatElyLilliinthe1950s,butmostlypub…

Lysergicacid2-butylamide(2-Butyllysergamide,LSB)isananalogueoriginallydevelopedbyRichardPiochatElyLilliinthe1950s,butmostlypublicisedthroughresearchconductedbytheteamledbyDavidE.NicholsatPurdueUniversityItisastructuralisomerwiththetwoethylgroupsontheamidenitrogenhavingbeenreplacedbyasinglebutylgroup,joinedatthe2-position.Itisoneofthefewlysegamidederivativestoexceedthepotencyinanimaldrugdiscriminationassays,withthe(R)isomerhavinganED50of33nmol/kgforproducingdrug-appropriateresponding,vs48nmol/kg.Thecorresponding(R)-2-pentylanaloguehashigheraffinityforthe5-HT1Aand5-HT2Areceptors,butislesspotentinproducingdrug-appropriateresponding,suggestingthatthebutylcompoundhasahigherefficacyatthereceptortarget.

品牌介绍
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